All Phenotypes Ppargc1b<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ppargc1b⁺
wild type
MGI:3049292

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Ppargc1a^tm1Dpk/Ppargc1a^tm1Dpk Ppargc1b^tm1.1Dpk/Ppargc1b⁺	involves: 129X1/SvJ * FVB/N	MGI:3802665

Allelic Composition	Ppargc1a^tm1Dpk/Ppargc1a^tm1Dpk Ppargc1b^tm1.1Dpk/Ppargc1b⁺
Genetic Background	involves: 129X1/SvJ * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppargc1a^tm1Dpk mutation (1 available); any Ppargc1a mutation (47 available)
Ppargc1b^tm1.1Dpk mutation (1 available); any Ppargc1b mutation (59 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

impaired adaptive thermogenesis ( J:137598 )

• mice exhibit reduced capacity to regulate core temperature after 2 hours of cold exposure compared to wild-type and Ppargc1b^tm1.1Dpk homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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