neoplasm
• papillomas begin to appear at 12 weeks post DMBA (7, 12-dimethylbenz(a) anthracene) and TPA (12-O-tetradecanoylphorbol-13-acetate) treatment compared to 15 weeks in wild-type mice
• the proportion of mice that develop papillomas after DMBA and TPA treatment is increased
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• the number of DMBA and TPA induced papillomas per mouse is markedly increased
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homeostasis/metabolism
• papillomas begin to appear at 12 weeks post DMBA (7, 12-dimethylbenz(a) anthracene) and TPA (12-O-tetradecanoylphorbol-13-acetate) treatment compared to 15 weeks in wild-type mice
• the proportion of mice that develop papillomas after DMBA and TPA treatment is increased
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integument
• the number of DMBA and TPA induced papillomas per mouse is markedly increased
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