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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Paqr3+
wild type
MGI:3049171
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Paqr3tm1Ychn/Paqr3+ involves: 129 * C57BL/6J MGI:4414762


Genotype
MGI:4414762
ht1
Allelic
Composition
Paqr3tm1Ychn/Paqr3+
Genetic
Background
involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Paqr3tm1Ychn mutation (0 available); any Paqr3 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• papillomas begin to appear at 12 weeks post DMBA (7, 12-dimethylbenz(a) anthracene) and TPA (12-O-tetradecanoylphorbol-13-acetate) treatment compared to 15 weeks in wild-type mice
• the proportion of mice that develop papillomas after DMBA and TPA treatment is increased
• the number of DMBA and TPA induced papillomas per mouse is markedly increased

homeostasis/metabolism
• papillomas begin to appear at 12 weeks post DMBA (7, 12-dimethylbenz(a) anthracene) and TPA (12-O-tetradecanoylphorbol-13-acetate) treatment compared to 15 weeks in wild-type mice
• the proportion of mice that develop papillomas after DMBA and TPA treatment is increased

integument
• the number of DMBA and TPA induced papillomas per mouse is markedly increased





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory