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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mtap+
wild type
MGI:3049037
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		MtapGt(RRK081)Byg/Mtap+ 129P2/OlaHsd-MtapGt(RRK081)Byg MGI:3719682
ht2
 		Mtapem1(IMPC)Mbp/Mtap+ C57BL/6N-Mtapem1(IMPC)Mbp/MbpMmucd MGI:6480515
ht3
 		MtapGt(RRK081)Byg/Mtap+ involves: 129P2/OlaHsd * CBA/CaJ MGI:3719687


Genotype
MGI:3719682
ht1
Allelic
Composition		 MtapGt(RRK081)Byg/Mtap+
Genetic
Background		 129P2/OlaHsd-MtapGt(RRK081)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MtapGt(RRK081)Byg mutation (1 available); any Mtap mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
arteritis ( J:123675 )
• at 4 to 7 months of age, some heterozygotes display polyarteritis nodosa; however, no consistent phenotype is observed

liver/biliary system
abnormal liver morphology ( J:123675 )
• at 4 to 7 months of age, some heterozygotes display unusual vacuoles in the liver; however, no consistent phenotype is observed

respiratory system
abnormal bronchus morphology ( J:123675 )
• at 4 to 7 months of age, some heterozygotes display dilated bronchi; however, no consistent phenotype is observed

immune system
arteritis ( J:123675 )
• at 4 to 7 months of age, some heterozygotes display polyarteritis nodosa; however, no consistent phenotype is observed

hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:123675 )
N
• at 5 and a half weeks of age, heterozygotes display normal cochlear function, with no significant differences in ABR and DPOAE thresholds relative to wild-type mice




Genotype
MGI:6480515
ht2
Allelic
Composition		 Mtapem1(IMPC)Mbp/Mtap+
Genetic
Background		 C57BL/6N-Mtapem1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mtapem1(IMPC)Mbp mutation (1 available); any Mtap mutation (17 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
enlarged thymus ( J:211773 )
IMPC - UCD

growth/size/body
enlarged spleen ( J:211773 )
IMPC - UCD

hematopoietic system
enlarged thymus ( J:211773 )
IMPC - UCD
enlarged spleen ( J:211773 )
IMPC - UCD

immune system
enlarged thymus ( J:211773 )
IMPC - UCD
enlarged spleen ( J:211773 )
IMPC - UCD

integument

liver/biliary system
small liver ( J:211773 )
IMPC - UCD

vision/eye
cataract ( J:211773 )
IMPC - UCD




Genotype
MGI:3719687
ht3
Allelic
Composition		 MtapGt(RRK081)Byg/Mtap+
Genetic
Background		 involves: 129P2/OlaHsd * CBA/CaJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MtapGt(RRK081)Byg mutation (1 available); any Mtap mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:123675 )
N
• at 5 and a half weeks and at 6 months of age, heterozygotes show no significant differences in ABR and DPOAE thresholds relative to wild-type mice




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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory