All Phenotypes Depdc5<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Depdc5⁺
wild type
MGI:3048359

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Depdc5^{tm1b(EUCOMM)Hmgu}/Depdc5⁺	C57BL/6N-Depdc5^{tm1b(EUCOMM)Hmgu}/H	MGI:5756982
cn2	Depdc5^{tm1c(EUCOMM)Hmgu}/Depdc5⁺ Tg(Syn1-cre)671Jxm/0	involves: C57BL/6N * CBA	MGI:6154994

Allelic Composition	Depdc5^{tm1b(EUCOMM)Hmgu}/Depdc5⁺
Genetic Background	C57BL/6N-Depdc5^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0734_3_G10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Depdc5^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Depdc5 mutation (120 available)

Data Sources

IMPC Data for Depdc5

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

impaired glucose tolerance ( J:211773 )

IMPC - HAR

Allelic Composition	Depdc5^{tm1c(EUCOMM)Hmgu}/Depdc5⁺ Tg(Syn1-cre)671Jxm/0
Genetic Background	involves: C57BL/6N * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Depdc5^{tm1c(EUCOMM)Hmgu} mutation (3 available); any Depdc5 mutation (120 available)
Tg(Syn1-cre)671Jxm mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body weight ( J:260943 )

• in male, but not female, mice after 3 months of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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