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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Bclaf1+
wild type
MGI:3048057
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Bclaf1tm1b(EUCOMM)Wtsi/Bclaf1+ B6N(Cg)-Bclaf1tm1b(EUCOMM)Wtsi/J MGI:6261969
ht2
Bclaf1tm1Raz/Bclaf1+ involves: 129P2/OlaHsd * C57BL/6 MGI:4438382


Genotype
MGI:6261969
ht1
Allelic
Composition
Bclaf1tm1b(EUCOMM)Wtsi/Bclaf1+
Genetic
Background
B6N(Cg)-Bclaf1tm1b(EUCOMM)Wtsi/J
Cell Lines EPD0599_4_C06
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bclaf1tm1b(EUCOMM)Wtsi mutation (1 available); any Bclaf1 mutation (62 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
IMPC - JAX

vision/eye




Genotype
MGI:4438382
ht2
Allelic
Composition
Bclaf1tm1Raz/Bclaf1+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bclaf1tm1Raz mutation (0 available); any Bclaf1 mutation (62 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• peripheral T cells exhibit reduced proliferation in response to anti-CD3 and anti-CD28 or anti-CD3 and IL2 unlike similarly treated wild-type cells

hematopoietic system
• peripheral T cells exhibit reduced proliferation in response to anti-CD3 and anti-CD28 or anti-CD3 and IL2 unlike similarly treated wild-type cells

cellular
• peripheral T cells exhibit reduced proliferation in response to anti-CD3 and anti-CD28 or anti-CD3 and IL2 unlike similarly treated wild-type cells





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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory