All Phenotypes Cyp17a1<tm1Mell> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cyp17a1^tm1Mell
targeted mutation 1, Synthia H Mellon
MGI:3047328

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cyp17a1^tm1Mell/Cyp17a1^tm1Mell	involves: 129X1/SvJ * C57BL/6	MGI:3047350

Allelic Composition	Cyp17a1^tm1Mell/Cyp17a1^tm1Mell
Genetic Background	involves: 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cyp17a1^tm1Mell mutation (0 available); any Cyp17a1 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:91081 )

• embryos die around E7

• supplementation with steroids (DHEA or androstenedione) does not rescue lethality in homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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