Phenotypes associated with this allele

• Allele Symbol: Tg(PDGFB-EPO)321Zbz
• Allele Name: transgene insertion 321, University of Zurich
• Allele ID: MGI:3047261
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Kit^W/Kit^W Tg(PDGFB-EPO)321Zbz/?	involves: C3H * C57BL/6	MGI:3714525

Genotype
MGI:3714525

cx1

• Allelic Composition: Kit^W/Kit^W; Tg(PDGFB-EPO)321Zbz/?
• Genetic Background: involves: C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased thymocyte number ( J:79128 )

• thymic TN-1 cells are lacking

abnormal B cell differentiation ( J:79128 )

• severe block to T cell and B cell development is similar to that seen in Kit^W-vkd homozygotes

abnormal T cell differentiation ( J:79128 )

• severe block to T cell and B cell development is similar to that seen in Kit^W-vkd homozygotes

decreased B cell number ( J:79128 )

• bone marrow fraction B cells are lacking

immune system

decreased thymocyte number ( J:79128 )

• thymic TN-1 cells are lacking

abnormal B cell differentiation ( J:79128 )

• severe block to T cell and B cell development is similar to that seen in Kit^W-vkd homozygotes

abnormal T cell differentiation ( J:79128 )

• severe block to T cell and B cell development is similar to that seen in Kit^W-vkd homozygotes

decreased B cell number ( J:79128 )

• bone marrow fraction B cells are lacking

endocrine/exocrine glands

decreased thymocyte number ( J:79128 )

• thymic TN-1 cells are lacking