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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pde3atm1Vman
targeted mutation 1, Vincent Manganiello
MGI:3046786
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pde3atm1Vman/Pde3atm1Vman either: (involves: 129X1/SvJ * C57BL/6J) or (involves: 129X1/SvJ * Black Swiss * C57BL/6J) MGI:3050153


Genotype
MGI:3050153
hm1
Allelic
Composition		 Pde3atm1Vman/Pde3atm1Vman
Genetic
Background		 either: (involves: 129X1/SvJ * C57BL/6J) or (involves: 129X1/SvJ * Black Swiss * C57BL/6J)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde3atm1Vman mutation (0 available); any Pde3a mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal female meiosis ( J:91348 )
• oocytes arrest in meiotic prophase I
female infertility ( J:91348 )
• females but not males are completely sterile

cellular
abnormal female meiosis ( J:91348 )
• oocytes arrest in meiotic prophase I




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory