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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Btlatm1Kay
targeted mutation 1, Jonathan Kaye
MGI:3045408
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Btlatm1Kay/Btlatm1Kay involves: 129S6/SvEvTac * C57BL/6J MGI:3045436


Genotype
MGI:3045436
hm1
Allelic
Composition		 Btlatm1Kay/Btlatm1Kay
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Btlatm1Kay mutation (1 available); any Btla mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell activation ( J:89864 )
• lymph node T cells are hyper-responsive to T cell receptor mediated activation
• peripheral lymphoid organ cell subpopulations are otherwise normal

hematopoietic system
abnormal T cell activation ( J:89864 )
• lymph node T cells are hyper-responsive to T cell receptor mediated activation
• peripheral lymphoid organ cell subpopulations are otherwise normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory