All Phenotypes Or8a1<tm2Mom> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Or8a1^tm2Mom
targeted mutation 2, Peter Mombaerts
MGI:3045137

Summary

8 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Or8a1^tm2Mom/Or8a1^tm26Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694129
ht2	Or8a1^tm2Mom/Or8a1^tm9Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694204
ht3	Or8a1^tm2Mom/Or8a1^tm10Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694206
ht4	Or8a1^tm2Mom/Or8a1^{tm11(Or8a1b)Mom}	involves: 129P2/OlaHsd * C57BL/6	MGI:3694131
ht5	Or8a1^tm2Mom/Or8a1^tm4Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694199
ht6	Or8a1^tm2Mom/Or8a1^tm8Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694203
cx7	Or8a1^tm2Mom/Or8a1⁺ Or8a1b^tm6Mom/Or8a1b⁺	involves: 129P2/OlaHsd * C57BL/6	MGI:3694130
cx8	Cnga2^tm1Mom/Cnga2^tm1Mom Or8a1^tm2Mom/Or8a1^tm4Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694207

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm26Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm26Mom mutation (3 available); any Or8a1 mutation (69 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:90716 )

abnormal olfactory neuron innervation pattern ( J:90716 )

• atypical glomeruli are formed in which some co-mingling of Olfr151^tm2Momaxons with both Olfr151 and Olfr160 axons occurs, but Olfr151^tm2Momaxons are shared between glomeruli

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm9Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm9Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb I axons segregate from Hyb B axons

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm10Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm10Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb F axons co-converge with but segregate from Hyb B axons

Allelic Composition	Or8a1^tm2Mom/Or8a1^{tm11(Or8a1b)Mom}
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^{tm11(Or8a1b)Mom} mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:90716 )

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb B axons co-converge to a large extent and co-mingle with Olfr151^{tm11(Olfr160)Mom} axons

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm4Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm4Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• axons co-converge without co-mingling, and segregate into separate compartments within the same glomeruli

• after naris occlusion before glomerular formation, axons still segregate into separate compartments within the same glomeruli, but there are supernumerary glomeruli

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm8Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm8Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb H axons segregate from Hyb B axons

Allelic Composition	Or8a1^tm2Mom/Or8a1⁺ Or8a1b^tm6Mom/Or8a1b⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1b^tm6Mom mutation (4 available); any Or8a1b mutation (35 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:90716 )

abnormal olfactory neuron innervation pattern ( J:90716 )

• Olfr151 and Olfr160 axons only intermingle to a small extent; atypical glomeruli are formed in which some co-mingling of Olfr151^tm2Momaxons with both Olfr151 and Olfr160 axons occurs, but Olfr151^tm2Momaxons are shared between glomeruli

Allelic Composition	Cnga2^tm1Mom/Cnga2^tm1Mom Or8a1^tm2Mom/Or8a1^tm4Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cnga2^tm1Mom mutation (2 available); any Cnga2 mutation (15 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm4Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb B and Hyb D axons segregate into separate into separate compartments within the same glomeruli

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