Analysis Tools
embryo
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• body length is reduced in homozygous embryos
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• marker expression patterns indicate that anterior-posterior polarity of the somites and lateral sclerotome is abnormal
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growth/size/body
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• body length is reduced in homozygous embryos
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skeleton
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• the proximal ribs are largely reduced or absent all along the vertebral column
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• a distorted rib cage is seen in homozygous mice
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• a small rib cage is seen in homozygous mice
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• pedicles are largely reduced or absent all along the vertebral column
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nervous system
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• at E10.5 spinal nerve appear less bundled with some single axons projecting laterally away from the bundle
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