All Phenotypes Sigmar1<tm1Lmon> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sigmar1^tm1Lmon
targeted mutation 1, Lluis Montoliu
MGI:3044771

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sigmar1^tm1Lmon/Sigmar1^tm1Lmon	either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	MGI:3044773

Allelic Composition	Sigmar1^tm1Lmon/Sigmar1^tm1Lmon
Genetic Background	either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sigmar1^tm1Lmon mutation (2 available); any Sigmar1 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased locomotor activity ( J:89669 )

• mean mobile time during spontaneous activity is significantly lower for homozygous mutants

• a receptor agonist (SKF-10 047) fails to induce hyperactivity in homozygous mutant mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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