Phenotypes associated with this allele

• Allele Symbol: Tnfsf4^{Ath1-C57BL/6J}
• Allele Name: C57BL/6J
• Allele ID: MGI:3044290
• Summary: 5 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Tnfsf4^Ath1-PERA/EiJ/Tnfsf4^Ath1-C57BL/6J	B6.PERA-Tnfsf4^Ath1-PERA/EiJ/Pgn	MGI:3576511
cx2	Tnfsf4^Ath1-C57BL/6J/Tnfsf4^Ath1-C57BL/6J Ath2^C57BL/6J/Ath2^C57BL/6J	involves: C3H/HeJ * C57BL/6J	MGI:3044377
cx3	Apoe^tm1Unc/Apoe^tm1Unc Tnfsf4^Ath1-C57BL/6J/Tnfsf4^Ath1-C57BL/6J	involves: C3H/HeJ * C57BL/6J	MGI:3819480
ot4	Tnfsf4^Ath1-C57BL/6J/?	involves: BALB/cJ * C57BL/6J	MGI:3044364
ot5	Tnfsf4^Ath1-C57BL/6J/?	involves: C3H/HeJ * C57BL/6J	MGI:3044365

Genotype
MGI:3576511

ht1

• Allelic Composition: Tnfsf4^{Ath1-PERA/EiJ}/Tnfsf4^{Ath1-C57BL/6J}
• Genetic Background: B6.PERA-Tnfsf4^{Ath1-PERA/EiJ}/Pgn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating HDL cholesterol level ( J:79722 )

• mice heterozygous for the PERA/EiJ allele exhibit higher HDL cholesterol levels than do those homozygous for the C57BL/6J allele

Genotype
MGI:3044377

cx2

• Allelic Composition: Tnfsf4^{Ath1-C57BL/6J}/Tnfsf4^{Ath1-C57BL/6J}; Ath2^C57BL/6J/Ath2^C57BL/6J
• Genetic Background: involves: C3H/HeJ * C57BL/6J

cardiovascular system

increased susceptibility to atherosclerosis ( J:9832 )

homeostasis/metabolism

decreased circulating HDL cholesterol level ( J:9832 )

Genotype
MGI:3819480

cx3

• Allelic Composition: Apoe^tm1Unc/Apoe^tm1Unc; Tnfsf4^{Ath1-C57BL/6J}/Tnfsf4^{Ath1-C57BL/6J}
• Genetic Background: involves: C3H/HeJ * C57BL/6J

cardiovascular system

atherosclerotic lesions ( J:140288 )

• increased aortic lesion area in female animals fed a high fat diet

Genotype
MGI:3044364

ot4

• Allelic Composition: Tnfsf4^{Ath1-C57BL/6J}/?
• Genetic Background: involves: BALB/cJ * C57BL/6J

cardiovascular system

abnormal cardiovascular system morphology ( J:8735 )

homeostasis/metabolism

abnormal lipid homeostasis ( J:8735 )

Genotype
MGI:3044365

ot5

• Allelic Composition: Tnfsf4^{Ath1-C57BL/6J}/?
• Genetic Background: involves: C3H/HeJ * C57BL/6J

cardiovascular system

increased susceptibility to atherosclerosis ( J:8735 )

homeostasis/metabolism

decreased circulating HDL cholesterol level ( J:8735 , J:9135 )