Phenotypes associated with this allele

• Allele Symbol: Prmt8⁺
• Allele Name: wild type
• Allele ID: MGI:3043084
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Prmt8^tm1d(EUCOMM)Wtsi/Prmt8^+	involves: C57BL/6N	MGI:5806918

Genotype
MGI:5806918

ht1

• Allelic Composition: Prmt8^{tm1d(EUCOMM)Wtsi}/Prmt8⁺
• Genetic Background: involves: C57BL/6N
• Cell Lines: EPD0105_1_A03

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

limb grasping ( J:234033 )

• at 10-14 weeks of age, 5% of heterozygotes clasp their hindlimbs when lifted by the tail versus 0% in wild-type controls

nervous system

abnormal cerebellum morphology ( J:234033 )

• in the cerebellum, choline levels are significantly decreased relative to those in wild-type controls

• however, acetylcholine and dipalmitoylphosphatidylcholine (DPPC) levels are not significantly altered