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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tir2C57BL/6JOlaHsd
C57BL/6JOlaHsd
MGI:3042256
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd A.B6-(D5Mit200-D5Mit10) MGI:3794643
hm2
 		Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd A.B6-Tir2 MGI:3578870
hm3
 		Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd involves: A/JOlaHsd * C57BL/6JOlaHsd MGI:3042258
hm4
 		Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd involves: BALB/cOlaHsd * C57BL/6JOlaHsd MGI:3042260
ht5
 		Tir2BALB/cOlaHsd/Tir2C57BL/6JOlaHsd involves: BALB/cOlaHsd * C57BL/6JOlaHsd MGI:3042259


Genotype
MGI:3794643
hm1
Allelic
Composition		 Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd
Genetic
Background		 A.B6-(D5Mit200-D5Mit10)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to parasitic infection ( J:135428 )
• this locus accounts for 21.5% of the phenotypic variance
• increased survival time (26.2 days longer) in the late phase of Trypanosome congolense infection




Genotype
MGI:3578870
hm2
Allelic
Composition		 Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd
Genetic
Background		 A.B6-Tir2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to parasitic infection ( J:97672 )
• mean survival time of 49.5 days following challenge with Trypanosome congolense




Genotype
MGI:3042258
hm3
Allelic
Composition		 Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd
Genetic
Background		 involves: A/JOlaHsd * C57BL/6JOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to parasitic infection ( J:40771 )
• resistance to infection by Trypanosome congolense




Genotype
MGI:3042260
hm4
Allelic
Composition		 Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd
Genetic
Background		 involves: BALB/cOlaHsd * C57BL/6JOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to parasitic infection ( J:40771 )
• resistance to infection by Trypanosome congolense




Genotype
MGI:3042259
ht5
Allelic
Composition		 Tir2BALB/cOlaHsd/Tir2C57BL/6JOlaHsd
Genetic
Background		 involves: BALB/cOlaHsd * C57BL/6JOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory