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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Setdb1tm1Enl
targeted mutation 1, En Li
MGI:3040431
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Setdb1tm1Enl/Setdb1tm1Enl involves: 129S4/SvJae MGI:3041276


Genotype
MGI:3041276
hm1
Allelic
Composition		 Setdb1tm1Enl/Setdb1tm1Enl
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Setdb1tm1Enl mutation (0 available); any Setdb1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:89058 )
• peri-implantation lethality between E3.5 and E5.5
• longest-surviving embryos die shortly after implantation

embryo
decreased inner cell mass proliferation ( J:89058 )
• impaired growth of the inner cell mass

cellular
decreased inner cell mass proliferation ( J:89058 )
• impaired growth of the inner cell mass




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory