Phenotypes associated with this allele

• Allele Symbol: Tg(Wap-HRAS)69Lln
• Allele Name: transgene insertion 69, Loretta L Nielsen
• Allele ID: MGI:3039648
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	X/Tg(Wap-HRAS)69Lln	FVB.Cg-Tg(Wap-HRAS)69Lln Chr Y^SJL/J	MGI:3844623
tg2	X/Tg(Wap-HRAS)69Lln	involves: C57BL/6 * SJL	MGI:3844620

Genotype
MGI:3844623

tg1

• Allelic Composition: X/Tg(Wap-HRAS)69Lln
• Genetic Background: FVB.Cg-Tg(Wap-HRAS)69Lln Chr Y^SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased mammary gland tumor incidence ( J:101113 )

♂ • by 3 months of age, mice develop between 1 and 4 mammary gland tumors

♂ • no metastasis is observed

endocrine/exocrine glands

increased mammary gland tumor incidence ( J:101113 )

♂ • by 3 months of age, mice develop between 1 and 4 mammary gland tumors

♂ • no metastasis is observed

integument

increased mammary gland tumor incidence ( J:101113 )

♂ • by 3 months of age, mice develop between 1 and 4 mammary gland tumors

♂ • no metastasis is observed

Genotype
MGI:3844620

tg2

• Allelic Composition: X/Tg(Wap-HRAS)69Lln
• Genetic Background: involves: C57BL/6 * SJL

neoplasm

increased mammary gland tumor incidence ( J:46458 )

♂

abnormal metastatic potential ( J:46458 )

♂ • 1 mouse of 13 exhibited metastasis to the lungs

increased adenocarcinoma incidence ( J:72262 )

♂ • at 9 months of age, 5 mice develop adenocarcinomas in the neck region

increased salivary adenocarcinoma incidence ( J:46458 )

♂

endocrine/exocrine glands

increased salivary adenocarcinoma incidence ( J:46458 )

♂

increased mammary gland tumor incidence ( J:46458 )

♂

integument

increased mammary gland tumor incidence ( J:46458 )

♂

digestive/alimentary system

increased salivary adenocarcinoma incidence ( J:46458 )

♂