All Phenotypes Cul7<tm1Jdec> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cul7^tm1Jdec
targeted mutation 1, James A DeCaprio
MGI:3039533

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cul7^tm1Jdec/Cul7^tm1Jdec	involves: C57BL/6 * CD-1	MGI:3039535

Allelic Composition	Cul7^tm1Jdec/Cul7^tm1Jdec
Genetic Background	involves: C57BL/6 * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cul7^tm1Jdec mutation (0 available); any Cul7 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mice die immediately after birth due respiratory distress

cardiovascular system

abnormal vascular development ( J:85161 )

hemorrhage ( J:85161 )

• dermal and hypodermal hemorrhaging is observed in fetuses during late gestation

embryo

decreased embryo size ( J:85161 )

• reduced growth putatively due to placental defects

abnormal placenta development ( J:85161 )

• impaired trophoblast lineage differentiation

• abnormal vascular structure

growth/size/body

decreased embryo size ( J:85161 )

• reduced growth putatively due to placental defects

respiratory system

respiratory distress ( J:85161 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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