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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Idd5C57BL/10SnJ
C57BL/10SnJ
MGI:3036897
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Idd3C57BL/10SnJ/Idd3C57BL/10SnJ
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ 		involves: C57BL/10 * NOD/MrkTac MGI:3036901
cx2
 		Idd3C57BL/6/Idd3C57BL/6
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ 		involves: C57BL/6 * C57BL/10SnJ * NOD MGI:2674234
cx3
 		Airetm1.1Doi/Airetm1.1Doi
Idd3C57BL/6/Idd3C57BL/6
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ 		NOD.Cg-Idd3C57BL/6 Idd5C57BL/10SnJ Airetm1.1Doi/Doi MGI:3793705


Genotype
MGI:3036901
cx1
Allelic
Composition		 Idd3C57BL/10SnJ/Idd3C57BL/10SnJ
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ
Genetic
Background		 involves: C57BL/10 * NOD/MrkTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd3C57BL/10SnJ mutation (0 available); any Idd3 mutation (12 available)
Idd5C57BL/10SnJ mutation (5 available); any Idd5 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
pancreas inflammation ( J:88667 )
• resistance to insulitis

homeostasis/metabolism
abnormal glucose homeostasis ( J:88667 )
• resistance to type 1 diabetes

immune system
pancreas inflammation ( J:88667 )
• resistance to insulitis




Genotype
MGI:2674234
cx2
Allelic
Composition		 Idd3C57BL/6/Idd3C57BL/6
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ
Genetic
Background		 involves: C57BL/6 * C57BL/10SnJ * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd3C57BL/6 mutation (5 available); any Idd3 mutation (12 available)
Idd5C57BL/10SnJ mutation (5 available); any Idd5 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal glucose homeostasis ( J:71276 )
• partial reversal of autoimmune exocrinopathy markers




Genotype
MGI:3793705
cx3
Allelic
Composition		 Airetm1.1Doi/Airetm1.1Doi
Idd3C57BL/6/Idd3C57BL/6
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ
Genetic
Background		 NOD.Cg-Idd3C57BL/6 Idd5C57BL/10SnJ Airetm1.1Doi/Doi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Airetm1.1Doi mutation (2 available); any Aire mutation (52 available)
Idd3C57BL/6 mutation (5 available); any Idd3 mutation (12 available)
Idd5C57BL/10SnJ mutation (5 available); any Idd5 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system

digestive/alimentary system

endocrine/exocrine glands
abnormal pancreas physiology ( J:107432 )
• Background Sensitivity: the pancreatitis associated with the Airetm1.1Doi allele on the NOD background is much less severe when these alleles of Idd3 and Idd5 are present
• Background Sensitivity: the gastritis associated with the Airetm1.1Doi allele on the NOD background is much less severe when these alleles of Idd3 and Idd5 are present




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory