All Phenotypes Kit<W-3Bao> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kit^W-3Bao
dominant spotting 3 Baojin
MGI:3033410

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kit^W-3Bao/Kit^W-3Bao	C57BL/6J-Kit^W-3Bao	MGI:3033441
hm2	Kit^W-3Bao/Kit^W-3Bao	involves: C57BL/6J	MGI:4822202
ht3	Kit^W-3Bao/Kit⁺	C57BL/6J-Kit^W-3Bao	MGI:3033447
ht4	Kit^W-3Bao/Kit⁺	involves: C57BL/6J	MGI:4822200

Allelic Composition	Kit^W-3Bao/Kit^W-3Bao
Genetic Background	C57BL/6J-Kit^W-3Bao

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-3Bao mutation (0 available); any Kit mutation (179 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

absent coat pigmentation ( J:88137 )

integument

absent coat pigmentation ( J:88137 )

Allelic Composition	Kit^W-3Bao/Kit^W-3Bao
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-3Bao mutation (0 available); any Kit mutation (179 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality ( J:163026 )

• no mice are present at weaning despite normal heart beat in mice at E18.5

reproductive system

abnormal primordial ovarian follicle morphology ( J:163026 )

• at E18.5

abnormal seminiferous tubule morphology ( J:163026 )

• at E18.5, seminiferous tubules are contorted unlike in wild-type mice

abnormal male reproductive system physiology ( J:163026 )

• at E18.5, spermatogenic cells fail to migrate into contorted seminiferous tubules unlike in wild-type mice

hematopoietic system

macrocytic anemia ( J:163026 )

• at E18.5

decreased erythrocyte cell number ( J:163026 )

• at E18.5

decreased hematocrit ( J:163026 )

• at E18.5

decreased hemoglobin content ( J:163026 )

• at E18.5

increased mean corpuscular hemoglobin ( J:163026 )

• at E18.5

increased mean corpuscular hemoglobin concentration ( J:163026 )

• at E18.5

macrocytosis ( J:163026 )

• at E18.5

growth/size/body

decreased fetal size ( J:163026 )

• at E16.5 and E18.5

endocrine/exocrine glands

abnormal primordial ovarian follicle morphology ( J:163026 )

• at E18.5

abnormal seminiferous tubule morphology ( J:163026 )

• at E18.5, seminiferous tubules are contorted unlike in wild-type mice

integument

pallor ( J:163026 )

• at E14.5, E16.5, and E18.5

Allelic Composition	Kit^W-3Bao/Kit⁺
Genetic Background	C57BL/6J-Kit^W-3Bao

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-3Bao mutation (0 available); any Kit mutation (179 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

variable body spotting ( J:88137 )

• extensive white trunk band and variable spotting elsewhere

integument

variable body spotting ( J:88137 )

• extensive white trunk band and variable spotting elsewhere

Allelic Composition	Kit^W-3Bao/Kit⁺
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-3Bao mutation (0 available); any Kit mutation (179 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal seminiferous tubule morphology ( J:163026 )

• a few seminiferous tubules are filled a diluted pink substance instead of speratogenic cells unlike in wild-type mice

• dysplastic seminiferous tubules are reduced in diameter compared to in wild-type mice

hematopoietic system

hematopoietic system phenotype ( J:163026 )

N	• at 2 months, mice exhibit normal peripheral red blood cell counts

endocrine/exocrine glands

abnormal seminiferous tubule morphology ( J:163026 )

• a few seminiferous tubules are filled a diluted pink substance instead of speratogenic cells unlike in wild-type mice

• dysplastic seminiferous tubules are reduced in diameter compared to in wild-type mice

pigmentation

white spotting ( J:163026 )

• mice exhibit white spots on the abdomen, white distal limbs, and white tipped tails unlike wild-type mice

belly spot ( J:163026 )

integument

white spotting ( J:163026 )

• mice exhibit white spots on the abdomen, white distal limbs, and white tipped tails unlike wild-type mice

belly spot ( J:163026 )

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