Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fhl2tm1Chen mutation
(0 available);
any
Fhl2 mutation
(16 available)
|
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normal phenotype
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• homozygous mice exhibit no discernable phenotype; mice are viable and fertile with normal cardiac development and physiology
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Allelic
Composition |
Fhl2tm1Chen/Fhl2+
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Genetic
Background |
involves: 129S1/Sv * 129X1/SvJ |
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fhl2tm1Chen mutation
(0 available);
any
Fhl2 mutation
(16 available)
|
|
|
cardiovascular system
|
|
• augmented hypertrophic response to Ang II
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• augmented fibrosis response to Ang II
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growth/size/body
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• augmented hypertrophic response to Ang II
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fhl2tm1Chen mutation
(0 available);
any
Fhl2 mutation
(16 available)
Rock2tm1.1Liao mutation
(0 available);
any
Rock2 mutation
(58 available)
|
|
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cardiovascular system
|
N |
• hypertrophic and fibrosis responses to Ang II are similar to controls
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Analysis Tools
