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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ift88fxo
flexo
MGI:3027342
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ift88fxo/Ift88fxo C3.B6J-Ift88fxo MGI:3580671
hm2
Ift88fxo/Ift88fxo involves: C3HeB/FeJ * C57BL/6J MGI:3027343
ht3
Ift88fxo/Ift88tm1Rpw involves: 129/Sv * C3HeB/FeJ * C57BL/6J MGI:3027344


Genotype
MGI:3580671
hm1
Allelic
Composition
Ift88fxo/Ift88fxo
Genetic
Background
C3.B6J-Ift88fxo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift88fxo mutation (1 available); any Ift88 mutation (48 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• development is arrested at E12.5-E13.5

nervous system
• lack of ventral midline groove in the neural plate
• sharp angle to mesencephalic flexure at E9.5-E10.5

limbs/digits/tail
• preaxial polydactyly

embryo
• lack of ventral midline groove in the neural plate




Genotype
MGI:3027343
hm2
Allelic
Composition
Ift88fxo/Ift88fxo
Genetic
Background
involves: C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift88fxo mutation (1 available); any Ift88 mutation (48 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

nervous system
• no floor plate in the caudal spinal cord

embryo
• left-right randomization
• no floor plate in the caudal spinal cord

limbs/digits/tail




Genotype
MGI:3027344
ht3
Allelic
Composition
Ift88fxo/Ift88tm1Rpw
Genetic
Background
involves: 129/Sv * C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift88fxo mutation (1 available); any Ift88 mutation (48 available)
Ift88tm1Rpw mutation (0 available); any Ift88 mutation (48 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

nervous system
• lack the ventral midline groove in the neural plate
• sharp angle to mesencephalic flexure at E9.5-E10.5

limbs/digits/tail
• preaxial polydactyly

embryo
• development is arrested at E12.5-E13.5
• lack the ventral midline groove in the neural plate





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory