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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Grxcr1pi-tde
tasmanian devil
MGI:2681910
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Grxcr1pi-tde/Grxcr1pi-tde Not Specified MGI:2681946


Genotype
MGI:2681946
hm1
Allelic
Composition
Grxcr1pi-tde/Grxcr1pi-tde
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grxcr1pi-tde mutation (1 available); any Grxcr1 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

hearing/vestibular/ear
• abnormal stereocilia development, with progressive disorganization
• degeneration of most cochlear hair cells by 7 months
• abnormal stereocilia development, with progressive disorganization
• vestibular hair cells ultimately die
• raised thresholds for cochlear nerve responses to sound

nervous system
• abnormal stereocilia development, with progressive disorganization
• degeneration of most cochlear hair cells by 7 months
• abnormal stereocilia development, with progressive disorganization
• vestibular hair cells ultimately die
• raised thresholds for cochlear nerve responses to sound





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory