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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(PLFSADA)2465Rkmb
transgene insertion 2465, Michael R Blackburn
MGI:2681791
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Adatm1Mw/Adatm1Mw
Tg(PLFSADA)2465Rkmb/0 		involves: 129S7/SvEvBrd * C57BL/6 * FVB/N MGI:2682599


Genotype
MGI:2682599
cx1
Allelic
Composition		 Adatm1Mw/Adatm1Mw
Tg(PLFSADA)2465Rkmb/0
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adatm1Mw mutation (3 available); any Ada mutation (31 available)
Tg(PLFSADA)2465Rkmb mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:29350 )
• rescue from severe, perinatally lethal respiratory distress seen in mice homozygous for Adatm1Mw
• no hepatocellular damage; rescued from perinatal lethality seen in homozygous mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/05/2025
MGI 6.24 		The Jackson Laboratory