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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nktcn1C57BL/6J
C57BL/6J
MGI:2681149
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nktcn1C57BL/6J/Nktcn1C57BL/6J involves: C57BL/6J * NOD.B6-(D6Mit105-D6Mit135) MGI:2681153
hm2
 		Nktcn1C57BL/6J/Nktcn1C57BL/6J NOD.B6-(D1Mit369-D1Mit155)(D6Mit105-D6Mit135) MGI:3818445
ht3
 		Nktcn1C57BL/6J/Nktcn1NOD/ShiLt involves: C57BL/6J * NOD.B6-(D6Mit105-D6Mit135) MGI:2681154


Genotype
MGI:2681153
hm1
Allelic
Composition		 Nktcn1C57BL/6J/Nktcn1C57BL/6J
Genetic
Background		 involves: C57BL/6J * NOD.B6-(D6Mit105-D6Mit135)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nktcn1C57BL/6J mutation (3 available); any Nktcn1 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased NK T cell number ( J:85376 )
• increased natural killer T cell numbers

immune system
increased NK T cell number ( J:85376 )
• increased natural killer T cell numbers




Genotype
MGI:3818445
hm2
Allelic
Composition		 Nktcn1C57BL/6J/Nktcn1C57BL/6J
Genetic
Background		 NOD.B6-(D1Mit369-D1Mit155)(D6Mit105-D6Mit135)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nktcn1C57BL/6J mutation (3 available); any Nktcn1 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal T cell differentiation ( J:137521 )
• increased cell surface expression of Slamf1 and Slamf6 proteins
increased NK T cell number ( J:137521 )
• increased number and proportion of invariant natural killer cells in thymus and spleen

immune system
abnormal T cell differentiation ( J:137521 )
• increased cell surface expression of Slamf1 and Slamf6 proteins
increased NK T cell number ( J:137521 )
• increased number and proportion of invariant natural killer cells in thymus and spleen




Genotype
MGI:2681154
ht3
Allelic
Composition		 Nktcn1C57BL/6J/Nktcn1NOD/ShiLt
Genetic
Background		 involves: C57BL/6J * NOD.B6-(D6Mit105-D6Mit135)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nktcn1C57BL/6J mutation (3 available); any Nktcn1 mutation (3 available)
Nktcn1NOD/ShiLt mutation (0 available); any Nktcn1 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased NK T cell number ( J:85376 )
• increased natural killer T cell numbers

immune system
increased NK T cell number ( J:85376 )
• increased natural killer T cell numbers




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory