All Phenotypes Sod1<tm1Cje> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sod1^tm1Cje
targeted mutation 1, Charles J Epstein
MGI:2680903

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sod1^tm1Cje/Sod1^tm1Cje	involves: C57BL/6J * CD-1	MGI:3625076

Allelic Composition	Sod1^tm1Cje/Sod1^tm1Cje
Genetic Background	involves: C57BL/6J * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sod1^tm1Cje mutation (1 available); any Sod1 mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

increased fibroblast apoptosis ( J:42265 )

• cultured fibroblasts from homozygous mice undergo apoptosis at 4-10 times control cultures

decreased fibroblast proliferation ( J:42265 )

• cultured fibroblasts from homozygous mice did not grow well in culture and exhibited a growth rate of only 25% of controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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