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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cplx2tm1Tyag
targeted mutation 1, Takeshi Yagi
MGI:2680035
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cplx2tm1Tyag/Cplx2tm1Tyag B6.Cg-Cplx2tm1Tyag MGI:3719642
hm2
 		Cplx2tm1Tyag/Cplx2tm1Tyag involves: C57BL/6 * CBA MGI:3719586


Genotype
MGI:3719642
hm1
Allelic
Composition		 Cplx2tm1Tyag/Cplx2tm1Tyag
Genetic
Background		 B6.Cg-Cplx2tm1Tyag
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cplx2tm1Tyag mutation (0 available); any Cplx2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
reduced long-term potentiation ( J:106335 )
• long term potential does not increase as in wild-type mice as the level of tetanic stimulation is increased and is less than wild-type at 100 Hz




Genotype
MGI:3719586
hm2
Allelic
Composition		 Cplx2tm1Tyag/Cplx2tm1Tyag
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cplx2tm1Tyag mutation (0 available); any Cplx2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
reduced long-term potentiation ( J:57368 )
• tetanic stimulated long term potentials in Sch/Com-CA1 and mossy-fiber-CA3 circuits are reduced




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory