Phenotypes associated with this allele

• Allele Symbol: Krt71^rco3
• Allele Name: reduced coat 3
• Allele ID: MGI:2679210
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Krt71^rco3/Krt71^rco3	C3HeB/FeJ-Krt71^rco3	MGI:2679298

Genotype
MGI:2679298

hm1

• Allelic Composition: Krt71^rco3/Krt71^rco3
• Genetic Background: C3HeB/FeJ-Krt71^rco3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

alopecia ( J:85980 )

• hair reduced ventrally, sparse on hindlimbs and around genital area

• sparse coat on trunk, less so in facial region

• severe and progressive hair loss

• first body coat fully grown by day 16, curly

• alopecia apparent after second follicle generation

focal dorsal hair loss ( J:85980 )

• dorsal alopecia is patchy

abnormal hair shaft morphology ( J:85980 )

• bent and twisted

• uniform hair diameter and round cross section

abnormal hair cortex morphology ( J:85980 )

• frequent kinks and twists of the cortex

abnormal hair follicle morphology ( J:85980 )

• round rather than bean-shaped large shafted hair follicles flanked by two zig-zag hair follicles

abnormal hair follicle inner root sheath morphology ( J:85980 )

• keratinization in Henle's layer of the inner root sheath either discontinuous or absent

• absence of normal intermediate filament bundles in Henle's and Huxley's layers of the inner root sheath

curly vibrissae ( J:85980 )

• curly vibrissae by day 9 after birth