Phenotypes associated with this allele

• Allele Symbol: Tas1r3^tm1Rfm
• Allele Name: targeted mutation 1, Robert F Margolskee
• Allele ID: MGI:2678581
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tas1r3^tm1Rfm/Tas1r3^tm1Rfm	involves: C57BL/6	MGI:2678583

Genotype
MGI:2678583

hm1

• Allelic Composition: Tas1r3^tm1Rfm/Tas1r3^tm1Rfm
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

taste/olfaction

abnormal sweet taste sensitivity ( J:85822 )

• loss of behavioral attraction to sweet tastants

• mutants avoid high concentrations of artificial sweeteners

• normal detection of bitter, sour and salty tastants

abnormal umami taste sensitivity ( J:85822 )

• loss of behavioral attraction to umami tastants

• normal morphology and numbers of taste receptor cells

nervous system

abnormal somatic nervous system physiology ( J:85822 )

• diminished nerve response elicited by sweet and umami tastants