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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Abca12+
wild type
MGI:2676313
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Abca12el12/Abca12+ involves: 129/Sv * C57BL/6 MGI:4461054


Genotype
MGI:4461054
ht1
Allelic
Composition		 Abca12el12/Abca12+
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abca12el12 mutation (0 available); any Abca12 mutation (133 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal lipid homeostasis ( J:161652 )
• unlike wild-type cells, fibroblasts accumulate lipid in the presence of the lipid donor acetylated LDL
decreased cholesterol efflux ( J:161652 )
• in fibroblasts exposed to an LXR agonist




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory