All Phenotypes Scn8a<nur14> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Scn8a^nur14
neurological 14
MGI:2671787

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Scn8a^nur14/Scn8a^nur14	C57BL/6J-Scn8a^nur14	MGI:3840662
hm2	Scn8a^nur14/Scn8a^nur14	involves: C57BL/6J	MGI:3027225
ht3	Scn8a^med-TgA4Bs/Scn8a^nur14	involves: C3H * C57BL/6J	MGI:3840663

Allelic Composition	Scn8a^nur14/Scn8a^nur14
Genetic Background	C57BL/6J-Scn8a^nur14

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^nur14 mutation (0 available); any Scn8a mutation (100 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:146758 )

• mice do not survive beyond 1 month of age

behavior/neurological

tremors ( J:146758 )

• pronounced

ataxia ( J:146758 )

• ataxic gait

hindlimb paralysis ( J:146758 )

• mice exhibit partial loss of hindlimb function by 2 weeks of age

Allelic Composition	Scn8a^nur14/Scn8a^nur14
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^nur14 mutation (0 available); any Scn8a mutation (100 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:85113 )

• animals do not live to weaning age

behavior/neurological

hindlimb paralysis ( J:85113 )

Allelic Composition	Scn8a^med-TgA4Bs/Scn8a^nur14
Genetic Background	involves: C3H * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^med-TgA4Bs mutation (0 available); any Scn8a mutation (100 available)
Scn8a^nur14 mutation (0 available); any Scn8a mutation (100 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality ( J:146758 )

• mice do not survive beyond weaning

behavior/neurological

tremors ( J:146758 )

ataxia ( J:146758 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24