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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ssrp1tm1Rul
targeted mutation 1, H Earl Ruley
MGI:2669951
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ssrp1tm1Rul/Ssrp1tm1Rul either: (involves: 129S4/SvJae * 129/Sv) or (involves: 129S4/SvJae * C57BL/6) MGI:2670596


Genotype
MGI:2670596
hm1
Allelic
Composition		 Ssrp1tm1Rul/Ssrp1tm1Rul
Genetic
Background		 either: (involves: 129S4/SvJae * 129/Sv) or (involves: 129S4/SvJae * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ssrp1tm1Rul mutation (0 available); any Ssrp1 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:84557 )
• no homozygous mutants born from intercrossed heterozygotes
• by E5.5 about 25% of decidua were nearly or completely resorbed suggesting that homozygotes died between implantation and E5.5

embryo
inner cell mass degeneration ( J:84557 )
• ICM derived from homozygous blastocycts all degenerate




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory