About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ssrp1tm1Rul
targeted mutation 1, H Earl Ruley
MGI:2669951
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ssrp1tm1Rul/Ssrp1tm1Rul either: (involves: 129S4/SvJae * 129/Sv) or (involves: 129S4/SvJae * C57BL/6) MGI:2670596


Genotype
MGI:2670596
hm1
Allelic
Composition		 Ssrp1tm1Rul/Ssrp1tm1Rul
Genetic
Background		 either: (involves: 129S4/SvJae * 129/Sv) or (involves: 129S4/SvJae * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ssrp1tm1Rul mutation (0 available); any Ssrp1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:84557 )
• no homozygous mutants born from intercrossed heterozygotes
• by E5.5 about 25% of decidua were nearly or completely resorbed suggesting that homozygotes died between implantation and E5.5

embryo
inner cell mass degeneration ( J:84557 )
• ICM derived from homozygous blastocycts all degenerate




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory