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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prkg1tm1Naw
targeted mutation 1, Hermann Nawrath
MGI:2668650
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prkg1tm1Naw/Prkg1tm1Naw either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) MGI:2668840


Genotype
MGI:2668840
hm1
Allelic
Composition		 Prkg1tm1Naw/Prkg1tm1Naw
Genetic
Background		 either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkg1tm1Naw mutation (0 available); any Prkg1 mutation (65 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
abnormal cardiac muscle contractility ( J:84611 )
• cGMP analogues reduce the force of contraction in cardiac muscle from juvenile controls but not from juvenile mutants

muscle
abnormal cardiac muscle contractility ( J:84611 )
• cGMP analogues reduce the force of contraction in cardiac muscle from juvenile controls but not from juvenile mutants




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory