Phenotypes associated with this allele

• Allele Symbol: Tg(Krt14-MYCER)2184C.1Fmw
• Allele Name: transgene insertion 2184C.1, Fiona M Watt
• Allele ID: MGI:2667449
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Krt14-MYCER)2184C.1Fmw/?	involves: C57BL/6 * CBA	MGI:2667464

Genotype
MGI:2667464

tg1

• Allelic Composition: Tg(Krt14-MYCER)2184C.1Fmw/?
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

enlarged sebaceous gland ( J:68931 )

• myc activation stimulates sebocyte differentiation at the expense of hair differentiation

integument

enlarged sebaceous gland ( J:68931 )

• myc activation stimulates sebocyte differentiation at the expense of hair differentiation

abnormal hair follicle morphology ( J:68931 )

• normal follicle architecture was disrupted

• hair follicles were often missing

abnormal skin condition ( J:68931 )

• skin of transgenic animals treated with 4-hydroxy tamoxifin became greasy and stiff compared to wild-type animals

increased skin stiffness ( J:68931 )

• skin of transgenic animals treated with 4-hydroxy tamoxifin became greasy and stiff compared to wild-type animals

thick skin ( J:68931 )

• the epidermis of transgenic animals was thicker than wild type