Phenotypes associated with this allele

• Allele Symbol: Ahr^b-2
• Allele Name: b-2 variant
• Allele ID: MGI:2667355
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ahr^b-2/Ahr^b-2	A/He	MGI:3776495
hm2	Ahr^b-2/Ahr^b-2	C3H/He	MGI:3776494

Genotype
MGI:3776495

hm1

• Allelic Composition: Ahr^b-2/Ahr^b-2
• Genetic Background: A/He

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to xenobiotic induced morbidity/mortality ( J:26440 )

• mice are susceptible to DMBA induced lethality

homeostasis/metabolism

increased susceptibility to xenobiotic induced morbidity/mortality ( J:26440 )

• mice are susceptible to DMBA induced lethality

increased physiological sensitivity to xenobiotic ( J:26440 )

• mice are susceptible to the pathological effects of DMBA and exhibit lethality, weight loss, peritonitis, decreased spleen weight, and decreased thymus weight

Genotype
MGI:3776494

hm2

• Allelic Composition: Ahr^b-2/Ahr^b-2
• Genetic Background: C3H/He

mortality/aging

increased susceptibility to xenobiotic induced morbidity/mortality ( J:26440 )

• mice are susceptible to DMBA induced lethality

homeostasis/metabolism

increased susceptibility to xenobiotic induced morbidity/mortality ( J:26440 )

• mice are susceptible to DMBA induced lethality

increased physiological sensitivity to xenobiotic ( J:26440 )

• mice are susceptible to the pathological effects of DMBA and exhibit lethality, weight loss, peritonitis, decreased spleen weight, and decreased thymus weight