About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hint1tm1.1Tpm
targeted mutation 1.1, Tomi P Makela
MGI:2663678
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hint1tm1.1Tpm/Hint1tm1.1Tpm involves: BALB/c * C57BL/6 MGI:2663679
cx2
 		Fhittm1Hbn/Fhittm1Hbn
Hint1tm1.1Tpm/Hint1tm1.1Tpm 		involves: 129X1/SvJ * BALB/c * C57BL/6 MGI:2663686
cx3
 		Fhittm1Hbn/Fhittm1Hbn
Hint1tm1.1Tpm/Hint1+ 		involves: 129X1/SvJ * BALB/c * C57BL/6 MGI:2663691


Genotype
MGI:2663679
hm1
Allelic
Composition		 Hint1tm1.1Tpm/Hint1tm1.1Tpm
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hint1tm1.1Tpm mutation (0 available); any Hint1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:83562 )
• homozygous mice exhibit no discernable phenotype; mice are viable and fertile with normal histology and pathology of various tissues




Genotype
MGI:2663686
cx2
Allelic
Composition		 Fhittm1Hbn/Fhittm1Hbn
Hint1tm1.1Tpm/Hint1tm1.1Tpm
Genetic
Background		 involves: 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fhittm1Hbn mutation (0 available); any Fhit mutation (23 available)
Hint1tm1.1Tpm mutation (0 available); any Hint1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor incidence ( J:83562 )
• a small number of extraintestinal tumors and neoplasias were observed; spectrum was similar to that noted in Fhit deficient mice




Genotype
MGI:2663691
cx3
Allelic
Composition		 Fhittm1Hbn/Fhittm1Hbn
Hint1tm1.1Tpm/Hint1+
Genetic
Background		 involves: 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fhittm1Hbn mutation (0 available); any Fhit mutation (23 available)
Hint1tm1.1Tpm mutation (0 available); any Hint1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor incidence ( J:83562 )
• a small number of extraintestinal tumors and neoplasias were observed; spectrum was similar to that noted in Fhit deficient mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory