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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hint1tm1.1Tpm
targeted mutation 1.1, Tomi P Makela
MGI:2663678
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hint1tm1.1Tpm/Hint1tm1.1Tpm involves: BALB/c * C57BL/6 MGI:2663679
cx2
 		Fhittm1Hbn/Fhittm1Hbn
Hint1tm1.1Tpm/Hint1tm1.1Tpm 		involves: 129X1/SvJ * BALB/c * C57BL/6 MGI:2663686
cx3
 		Fhittm1Hbn/Fhittm1Hbn
Hint1tm1.1Tpm/Hint1+ 		involves: 129X1/SvJ * BALB/c * C57BL/6 MGI:2663691


Genotype
MGI:2663679
hm1
Allelic
Composition		 Hint1tm1.1Tpm/Hint1tm1.1Tpm
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hint1tm1.1Tpm mutation (0 available); any Hint1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:83562 )
• homozygous mice exhibit no discernable phenotype; mice are viable and fertile with normal histology and pathology of various tissues




Genotype
MGI:2663686
cx2
Allelic
Composition		 Fhittm1Hbn/Fhittm1Hbn
Hint1tm1.1Tpm/Hint1tm1.1Tpm
Genetic
Background		 involves: 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fhittm1Hbn mutation (0 available); any Fhit mutation (22 available)
Hint1tm1.1Tpm mutation (0 available); any Hint1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor incidence ( J:83562 )
• a small number of extraintestinal tumors and neoplasias were observed; spectrum was similar to that noted in Fhit deficient mice




Genotype
MGI:2663691
cx3
Allelic
Composition		 Fhittm1Hbn/Fhittm1Hbn
Hint1tm1.1Tpm/Hint1+
Genetic
Background		 involves: 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fhittm1Hbn mutation (0 available); any Fhit mutation (22 available)
Hint1tm1.1Tpm mutation (0 available); any Hint1 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor incidence ( J:83562 )
• a small number of extraintestinal tumors and neoplasias were observed; spectrum was similar to that noted in Fhit deficient mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory