Phenotypes associated with this allele

• Allele Symbol: Slc27a2^tm1Kds
• Allele Name: targeted mutation 1, Kirby D Smith
• Allele ID: MGI:2663647
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc27a2^tm1Kds/Slc27a2^tm1Kds	involves: 129S4/SvJae * 129S6/SvEvTac	MGI:2663648
cx2	Abcd1^tm1Kds/Abcd1^tm1Kds Slc27a2^tm1Kds/Slc27a2^tm1Kds	involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J	MGI:3029427
cx3	Abcd1^tm1Kds/Y Slc27a2^tm1Kds/Slc27a2^tm1Kds	involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J	MGI:3029429

Genotype
MGI:2663648

hm1

• Allelic Composition: Slc27a2^tm1Kds/Slc27a2^tm1Kds
• Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:83438 )

• normal behavior, viable and fertile

• histological analysis of mutant mouse liver, brain and kidney indicated that no significant abnormalities were present

cellular

abnormal cell physiology ( J:83438 )

• decreased peroxisomal very long-chain acyl-CoA synthetase activity and very long-chain fatty acid beta-oxidation

• very long-chain fatty acids do not accumulate

Genotype
MGI:3029427

cx2

• Allelic Composition: Abcd1^tm1Kds/Abcd1^tm1Kds; Slc27a2^tm1Kds/Slc27a2^tm1Kds
• Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J

normal phenotype

no abnormal phenotype detected ( J:83438 )

♀ • these mice were indistinguishable from wild-type

Genotype
MGI:3029429

cx3

• Allelic Composition: Abcd1^tm1Kds/Y; Slc27a2^tm1Kds/Slc27a2^tm1Kds
• Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J

normal phenotype

no abnormal phenotype detected ( J:83438 )

♂ • these mice were indistinguishable from wild-type