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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ntm+
wild type
MGI:2661211
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Ntmtm1Lex/Ntm+ involves: 129S5/SvEvBrd * C57BL/6 MGI:6278111
cx2
 		Ntmtm1.1Pagr/Ntm+
Opcmltm1.1Pagr/Opcml+ 		involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ MGI:6469760


Genotype
MGI:6278111
ht1
Allelic
Composition		 Ntmtm1Lex/Ntm+
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntmtm1Lex mutation (2 available); any Ntm mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired behavioral response to amphetamine ( J:249103 )
• heterozygotes exhibit decreased sensitivity to the locomotor stimulating effects of amphetamine (5 mg/kg) relative to wild-type control mice
• however, no differences are observed in the active avoidance task




Genotype
MGI:6469760
cx2
Allelic
Composition		 Ntmtm1.1Pagr/Ntm+
Opcmltm1.1Pagr/Opcml+
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntmtm1.1Pagr mutation (0 available); any Ntm mutation (23 available)
Opcmltm1.1Pagr mutation (0 available); any Opcml mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:294154 )
N
• normal cardiac structure at age 3 months




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory