Phenotypes associated with this allele

• Allele Symbol: Tg(Hbb-b1)83Clo
• Allele Name: transgene insertion 83, Cecilia W Lo
• Allele ID: MGI:2655271
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Pax6^Sey/Pax6^Sey-Neu Tg(Hbb-b1)83Clo/0	involves: 102 * C3H * C57BL * CBA/Ca * CD-1 * SJL	MGI:3771027
cx2	Pax6^Sey/Pax6^Sey Tg(Hbb-b1)83Clo/0	involves: C57BL * CBA/Ca * CD-1 * SJL	MGI:3771026

Genotype
MGI:3771027

cx1

• Allelic Composition: Pax6^Sey/Pax6^Sey-Neu; Tg(Hbb-b1)83Clo/0
• Genetic Background: involves: 102 * C3H * C57BL * CBA/Ca * CD-1 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial bone morphology ( J:43913 )

• all mice exhibit a median cartilaginous rod unlike wild-type mice

supernumerary incisors ( J:43913 )

• 22% of mice possess a single supernumerary upper incisor tooth

abnormal nasal capsule morphology ( J:43913 )

• 22% of mice posses unilateral or bilateral ectopic cartilaginous spurs derived from the antero-lateral aspect of the nasal capsule

respiratory system

abnormal nasal capsule morphology ( J:43913 )

• 22% of mice posses unilateral or bilateral ectopic cartilaginous spurs derived from the antero-lateral aspect of the nasal capsule

skeleton

abnormal craniofacial bone morphology ( J:43913 )

• all mice exhibit a median cartilaginous rod unlike wild-type mice

supernumerary incisors ( J:43913 )

• 22% of mice possess a single supernumerary upper incisor tooth

abnormal nasal capsule morphology ( J:43913 )

• 22% of mice posses unilateral or bilateral ectopic cartilaginous spurs derived from the antero-lateral aspect of the nasal capsule

growth/size/body

supernumerary incisors ( J:43913 )

• 22% of mice possess a single supernumerary upper incisor tooth

abnormal nasal capsule morphology ( J:43913 )

• 22% of mice posses unilateral or bilateral ectopic cartilaginous spurs derived from the antero-lateral aspect of the nasal capsule

Genotype
MGI:3771026

cx2

• Allelic Composition: Pax6^Sey/Pax6^Sey; Tg(Hbb-b1)83Clo/0
• Genetic Background: involves: C57BL * CBA/Ca * CD-1 * SJL

craniofacial

abnormal craniofacial bone morphology ( J:43913 )

• all mice exhibit a median cartilaginous rod unlike wild-type mice

supernumerary incisors ( J:43913 )

• 43% of mice from the agouti sub-line exhibit supernumerary upper incisor teeth and 14% of the non-agouti line possess a single supernumerary upper incisor tooth

abnormal nasal capsule morphology ( J:43913 )

• 86% mice from the agouti sub-line, but none from the non-agouti sub-line, posses unilateral or bilateral ectopic cartilaginous spurs derived from the antero-lateral aspect of the nasal capsule

respiratory system

abnormal nasal capsule morphology ( J:43913 )

• 86% mice from the agouti sub-line, but none from the non-agouti sub-line, posses unilateral or bilateral ectopic cartilaginous spurs derived from the antero-lateral aspect of the nasal capsule

skeleton

abnormal craniofacial bone morphology ( J:43913 )

• all mice exhibit a median cartilaginous rod unlike wild-type mice

supernumerary incisors ( J:43913 )

• 43% of mice from the agouti sub-line exhibit supernumerary upper incisor teeth and 14% of the non-agouti line possess a single supernumerary upper incisor tooth

abnormal nasal capsule morphology ( J:43913 )

• 86% mice from the agouti sub-line, but none from the non-agouti sub-line, posses unilateral or bilateral ectopic cartilaginous spurs derived from the antero-lateral aspect of the nasal capsule

growth/size/body

supernumerary incisors ( J:43913 )

• 43% of mice from the agouti sub-line exhibit supernumerary upper incisor teeth and 14% of the non-agouti line possess a single supernumerary upper incisor tooth

abnormal nasal capsule morphology ( J:43913 )

• 86% mice from the agouti sub-line, but none from the non-agouti sub-line, posses unilateral or bilateral ectopic cartilaginous spurs derived from the antero-lateral aspect of the nasal capsule