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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr308tm2Fwa
targeted mutation 1, Frederick W Alt
MGI:2654481
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr308tm2Fwa/Rr308tm2Fwa Not Specified MGI:2654484


Genotype
MGI:2654484
hm1
Allelic
Composition		 Rr308tm2Fwa/Rr308tm2Fwa
Genetic
Background		 Not Specified
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal T cell differentiation ( J:82395 )
• alpha beta T cell development is blocked at the double postive thymocyte stage, with low numbers of peripheral alpha beta T cells that express only Valpha2 gene segments and low numbers of peripheral alpha beta T cells expressing other Valpha's

immune system
abnormal T cell differentiation ( J:82395 )
• alpha beta T cell development is blocked at the double postive thymocyte stage, with low numbers of peripheral alpha beta T cells that express only Valpha2 gene segments and low numbers of peripheral alpha beta T cells expressing other Valpha's




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory