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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dppa4+
wild type
MGI:2653591
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Dppa4tm1.2Reik/Dppa4+ involves: C57BL/6 * FVB/N MGI:6845066
cn2
 		Dppa4tm1.1Reik/Dppa4+
Tmem163Tg(ACTB-cre)2Mrt/Tmem163+ 		involves: C57BL/6 * FVB/N MGI:6845064


Genotype
MGI:6845066
ht1
Allelic
Composition		 Dppa4tm1.2Reik/Dppa4+
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dppa4tm1.2Reik mutation (0 available); any Dppa4 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
maternal effect ( J:316936 )
• fewer offspring are produced from female mice




Genotype
MGI:6845064
cn2
Allelic
Composition		 Dppa4tm1.1Reik/Dppa4+
Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dppa4tm1.1Reik mutation (0 available); any Dppa4 mutation (31 available)
Tmem163Tg(ACTB-cre)2Mrt mutation (3 available); any Tmem163 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
maternal effect ( J:316936 )
• mice mated to null male mice exhibit loss of offspring prior to or immediately after birth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory