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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Erbb2tm1Vrtn
targeted mutation 1, Timothy Vartanian
MGI:2651799
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Erbb2tm1Vrtn/Erbb2tm1Vrtn Not Specified MGI:2651800


Genotype
MGI:2651800
hm1
Allelic
Composition
Erbb2tm1Vrtn/Erbb2tm1Vrtn
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Erbb2tm1Vrtn mutation (0 available); any Erbb2 mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

nervous system
• oligodendrocyte development is arrested at the proligodendroblast stage in spinal cord explants from E9.5 embryos, with a greater than 10-fold reduction in the number of galactosylcerebroside-positive oligodendroctyes
• of the oligodendrocytes that do differentiate, all fail to ensheath neurites





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory