Phenotypes associated with this allele

• Allele Symbol: Lipi^lpd1
• Allele Name: lipid defect
• Allele ID: MGI:2450247
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lipi^lpd1/Lipi^lpd1	involves: CD-1	MGI:3045800

Genotype
MGI:3045800

hm1

• Allelic Composition: Lipi^lpd1/Lipi^lpd1
• Genetic Background: involves: CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality ( J:46789 )

• death by 10 to 15 days of age

behavior/neurological

tremors ( J:46789 )

• generalized tremor developing 5 to 10 days after birth

abnormal gait ( J:46789 )

• unsteady gait developing 5 to 10 days after birth

growth/size/body

decreased body size ( J:46789 )

• not a result from a failure to nurse, as milk was observed in the stomach

decreased body weight ( J:46789 )

• exhibited ~3 days after birth

homeostasis/metabolism

increased circulating triglyceride level ( J:46789 )

• 2 to 3 fold increase in plasma triglyceride levels, whereas plasma cholesterol levels were normal

increased liver triglyceride level ( J:46789 )

• increased hepatic triglyceride level, whereas hepatic cholesterol levels were normal

liver/biliary system

increased liver triglyceride level ( J:46789 )

• increased hepatic triglyceride level, whereas hepatic cholesterol levels were normal

hepatic steatosis ( J:46789 )

• numerous lipid-containing vacuoles with extensive triglyceride accumulation

• in severe cases, only ~20% of normal hepatic structure was left

integument

retarded hair growth ( J:46789 )