Phenotypes associated with this allele

• Allele Symbol: Tenm4^l7Rn3-2R
• Allele Name: mutation 2, Oak Ridge
• Allele ID: MGI:2449635
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tenm4^l7Rn3-2R/Tenm4^l7Rn3-2R	FRCH.Cg-Tenm4^l7Rn3-2R	MGI:3789291
hm2	Tenm4^l7Rn3-2R/Tenm4^l7Rn3-2R	involves: BALB/cRl * C3H/Rl * C57BL/10Rl	MGI:2449636

Genotype
MGI:3789291

hm1

• Allelic Composition: Tenm4^l7Rn3-2R/Tenm4^l7Rn3-2R
• Genetic Background: FRCH.Cg-Tenm4^l7Rn3-2R

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:96673 )

• mutants arrest at E6.5 before primitive streak formation, are resorbing by E9.5 and do not form embryonic or extraembryonic mesoderm; an A-P axis is also not apparent

embryo

abnormal rostral-caudal axis patterning ( J:96673 )

• an A-P axis is not observed

embryonic growth arrest ( J:96673 )

• mutant embryos exhibit growth arrest at E6.5 with an appearance similar to a pregastrulation stage embryo

absent mesoderm ( J:96673 )

• mutants do not form embryonic or extraembryonic mesoderm

Genotype
MGI:2449636

hm2

• Allelic Composition: Tenm4^l7Rn3-2R/Tenm4^l7Rn3-2R
• Genetic Background: involves: BALB/cRl * C3H/Rl * C57BL/10Rl

mortality/aging

prenatal lethality, complete penetrance ( J:54592 )