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Allele Symbol Allele Name Allele ID |
Tg(Mpz)80.3Wra transgene insertion 80.3, Lawrence Wrabetz MGI:2447696 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• dysmyelination is observed in P28 mutants
• ventral roots are more dysmyelinated than dorsal roots
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• sciatic nerves are hypomyelinated between P15 and P21, but by P28, nerves contain normal myelin
• ventral roots are more dysmyelinated than dorsal roots
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| N |
• mice appear behaviorally normal and show no tremors
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| N |
• mice have a median life span of more than 2 years
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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