Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
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nervous system
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• develop pathology with much faster onset of about 2 months compared to hemizygous transgenic mice
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behavior/neurological
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
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behavior/neurological
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• frequent scratching at 5-12 months of age
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• mild ataxia after 12 months of age
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growth/size/body
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• weight loss several weeks after one year of age
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nervous system
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• massive neuronal loss in the cerebellar granular layer and the molecular layer, however Purkinje neurons are not affected
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integument
Analysis Tools