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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(BGLAP-PTN)1Thg
transgene insertion 1, Tamotsu Hashimoto-Gotoh
MGI:2446540
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(BGLAP-PTN)1Thg/Tg(BGLAP-PTN)1Thg involves: C57BL/6 * DBA/1 MGI:2652098
tg2
Tg(BGLAP-PTN)1Thg/0 involves: C57BL/6 * DBA/1 MGI:2652095


Genotype
MGI:2652098
tg1
Allelic
Composition
Tg(BGLAP-PTN)1Thg/Tg(BGLAP-PTN)1Thg
Genetic
Background
involves: C57BL/6 * DBA/1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(BGLAP-PTN)1Thg mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• increased in females; however, 14 weeks after ovarectomy, bone mineral content was comparable to that of unovarectomized wild-type mice




Genotype
MGI:2652095
tg2
Allelic
Composition
Tg(BGLAP-PTN)1Thg/0
Genetic
Background
involves: C57BL/6 * DBA/1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(BGLAP-PTN)1Thg mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• increased thickness of calvaria bones
• male animals show increased bone mineral content at 15, 25, and 30 weeks of age
• reduced rate of bone growth
• absence of pubertal growth spurt
• extended duration of bone growth (25 weeks)

craniofacial
• increased thickness of calvaria bones

limbs/digits/tail





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory