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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mybl2tm1Sis
targeted mutation 1, Shunsuke Ishii
MGI:2445746
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mybl2tm1Sis/Mybl2tm1Sis involves: C57BL/6 * CBA MGI:3528088


Genotype
MGI:3528088
hm1
Allelic
Composition		 Mybl2tm1Sis/Mybl2tm1Sis
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mybl2tm1Sis mutation (1 available); any Mybl2 mutation (116 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:57999 )
• shortly after uterine implantation, between E3.5 and E6.5

embryo
abnormal inner cell mass morphology ( J:57999 )
• little or no development of the inner cell mass in cultured embryos
• however, the trophectoderm develops normally




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory