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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Actb-Tnfsf4)1Nish
transgene insertion 1, Naoto Ishii
MGI:2445589
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Actb-Tnfsf4)1Nish/0 B6.D2-Tg(Actb-Tnfsf4)1Nish MGI:2651596


Genotype
MGI:2651596
tg1
Allelic
Composition		 Tg(Actb-Tnfsf4)1Nish/0
Genetic
Background		 B6.D2-Tg(Actb-Tnfsf4)1Nish
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased T cell proliferation ( J:80214 )
• increased hapten-specific T cell proliferative response
increased susceptibility to type IV hypersensitivity reaction ( J:80214 )
• increased ear swelling 24 hours following challenge with 4-dinitrofluorobenzene (DNFB), 6-trinitrochlorobenzene (TNCB), and FITC compared to wild-type
abnormal cytokine secretion ( J:80214 )
• increased hapten-specific cytokine production

hematopoietic system
increased T cell proliferation ( J:80214 )
• increased hapten-specific T cell proliferative response

cellular
increased T cell proliferation ( J:80214 )
• increased hapten-specific T cell proliferative response




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory