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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Optn+
wild type
MGI:2440703
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Optnem1Hyua/Optn+ C57BL/6J-Optnem1Hyua MGI:7531850
ht2
 		Optntm1a(EUCOMM)Wtsi/Optn+ C57BL/6N-Optntm1a(EUCOMM)Wtsi/Ieg MGI:5782150


Genotype
MGI:7531850
ht1
Allelic
Composition		 Optnem1Hyua/Optn+
Genetic
Background		 C57BL/6J-Optnem1Hyua
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Optnem1Hyua mutation (0 available); any Optn mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired coordination ( J:303304 )
• shorter latency to fall in rotarod test at age 24 months
• normal latency to fall in rotarod test at age 16 months




Genotype
MGI:5782150
ht2
Allelic
Composition		 Optntm1a(EUCOMM)Wtsi/Optn+
Genetic
Background		 C57BL/6N-Optntm1a(EUCOMM)Wtsi/Ieg
Cell Lines EPD0116_2_A05
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Optntm1a(EUCOMM)Wtsi mutation (3 available); any Optn mutation (51 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory